Somatostatin interneurons in the prefrontal cortex control affective state discrimination in mice
The prefrontal cortex (PFC) is implicated in processing of the affective state of others through non-verbal communication. This social cognitive function is thought to…
Scheggia D et al. | Nature Neuroscience | December 16, 2019
A cortical-brainstem circuit predicts and governs compulsive alcohol drinking
What individual differences in neural activity predict the future escalation of alcohol drinking from casual to compulsive? The neurobiological mechanisms that gate the…
Siciliano CA et al. | Science | November 22, 2019
Novel nose poke-based temporal discrimination tasks with concurrent in vivo calcium imaging in freely moving mice
The hippocampus has been known to process temporal information as part of memory formation. While time cells have been observed in the hippocampus and medial entorhinal…
Marks WD et al. | Molecular Brain | November 6, 2019
Adaptive disinhibitory gating by VIP interneurons permits associative learning
Learning drives behavioral adaptations necessary for survival. While plasticity of excitatory projection neurons during associative learning has been extensively studied…
Krabbe S et al. | Nature Neuroscience | October 21, 2019
Revealing neural correlates of behavior without behavioral measurements
Measuring neuronal tuning curves has been instrumental for many discoveries in neuroscience but requires a priori assumptions regarding the identity of the encoded…
Rubin A et al. | Nature Communications | October 18, 2019
Cortical ensemble activity discriminates auditory attentional states
Selective attention modulates sensory cortical activity. It remains unclear how auditory cortical activity represents stimuli that differ behaviorally. We designed a…
Yao P-t et al. | Molecular Brain | October 17, 2019