Model-based behavioral control can predict future states based on chosen actions
Akam T et al. | Neuron | November 4, 2020Functional clusters track parallel processing in direct and indirect pathways
Shin JH et al. | PNAS | October 27, 2020
Mouse fMRI reveals affective computations in a corticolimbic loop
Kargl D et al. | eLife | October 20, 2020
Identification of a key cellular component of sleep homeostasis in mice
Ingiosi AM et al. | Current Biology | September 24, 2020
Slow neuronal dynamics encode threat responses for emotional memory
Kennedy A et al. | Nature | September 16, 2020
Microendoscopic calcium imaging of the primary visual cortex of behaving macaques
In vivo calcium imaging with genetically encoded indicators has recently been applied to macaque brains to monitor neural activities from a large population of cells…
Oguchi M et al. | Scientific Reports | August 23, 2021
Accumbens D2-MSN hyperactivity drives antipsychotic-induced behavioral supersensitivity
Antipsychotic-induced dopamine supersensitivity, or behavioral supersensitivity, is a problematic consequence of long-term antipsychotic treatment characterized by the…
Kruyer A et al. | Molecular Psychiatry | August 4, 2021
Optical deep-cortex exploration in behaving rhesus macaques
Non-human primates (NHPs) are important animal models for understanding higher brain functions relevant to complex human behaviors including cognition and motor control…
Matsuzaki M et al. | Nature Communications | August 2, 2021
Miniature microscopes for manipulating and recording in vivo brain activity
Here we describe the development and application of miniature integrated microscopes (miniscopes) paired with microendoscopes that allow for the visualization and…
Stamatakis AM et al. | Microscopy | August 2, 2021Complete representation of action space and value in all dorsal striatal pathways
The dorsal striatum plays a central role in the selection, execution, and evaluation of actions. An emerging model attributes action selection to the matrix and…
Weglage M et al. | Cell Reports | July 27, 2021
Reverse optogenetics of G protein signaling by zebrafish non-visual opsin Opn7b for synchronization of neuronal networks
Opn7b is a non-visual G protein-coupled receptor expressed in zebrafish. Here we find that Opn7b expressed in HEK cells constitutively activates the Gi/o pathway and…
Karapinar R et al. | Nature Communications | July 23, 2021