Parental behaviors secure the well-being of newborns and concomitantly limit negative affective states in adults, which emerge when coping with neonatal distress becomes challenging. Whether negative-affect-related neuronal circuits orchestrate parental actions is unknown. Here…

Lecca S et al. | Neuron | February 1, 2023

Transient sexual experiences can have long-lasting effects on behavioral…

ZHOU X et al. | Science | February 9, 2023

Pleasurable touch is paramount during social behavior, including sexual…

Elias LJ et al. | Cell | February 2, 2023

While there is emerging evidence of sex differences in decision-making behavior…

Cox J et al. | Nature Neuroscience | February 16, 2023

The hypothalamus regulates innate social behaviors, including mating and…

Nair A et al. | Cell | January 11, 2023
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Long-range inhibition synchronizes and updates prefrontal task activity

Changes in patterns of activity within the medial prefrontal cortex enable rodents,non-human primates and humans to update their behaviour to adapt to changes in the…

Cho KKA et al. | Nature | May 3, 2023

Control of contextual memory through interneuronal a5-GABAA receptors

γ-Aminobutyric acid type A receptors that incorporate α5 subunits (α5-GABAARs) are highly enriched in the hippocampus and are strongly implicated in control of learning…

Zhu M et al. | PNAS Nexus | April 11, 2023

Identification of an essential spinoparabrachial pathway for mechanical itch

The study identified a specific population of neurons that transmit mechanical itch from the spinal cord to the parabrachial nucleus (PBN) in the brain, and separate…

Ren X et al. | Neuron | April 5, 2023

Oxytocin promotes prefrontal population activity via the PVN-PFC pathway to regulate pain

Liu et al. conducted a study on rats to investigate the neural mechanisms involved in pain processing and modulation. Using behavioral assays and calcium imaging…

Liu Y et al. | Neuron | April 4, 2023

Lateral hypothalamic leptin receptor neurons drive hunger-gated food-seeking and consummatory behaviours in male mice

For survival, it is crucial for eating behaviours to be sequenced through two distinct seeking and consummatory phases. Heterogeneous lateral hypothalamus (LH) neurons…

Lee YH et al. | Nature Communications | March 17, 2023

Complementary lateral hypothalamic populations resist hunger pressure to balance nutritional and social needs

Animals continuously weigh hunger and thirst against competing needs, such as social contact and mating, according to state and opportunity. Yet neuronal mechanisms of…

Petzold A et al. | Cell Metabolism | February 23, 2023

bioRxiv Wire

Lateral parabrachial Kaur I et al. | May 5, 2023

Although CGRP neurons in the external lateral parabrachial…

Sex differences in Murugan I et al. | March 10, 2023

The reinforcing nature of social interactions is necessary…

Serotonin in the Hyun I et al. | March 9, 2023

Cognitive flexibility is the ability of the brain to switch…

An approximate line Nair A et al. | June 2, 2022

The hypothalamus plays a key role in regulating innate…