Parental behaviors secure the well-being of newborns and concomitantly limit negative affective states in adults, which emerge when coping with neonatal distress becomes challenging. Whether negative-affect-related neuronal circuits orchestrate parental actions is unknown. Here…
Lecca S et al. | Neuron | February 1, 2023Transient sexual experiences can have long-lasting effects on behavioral…
ZHOU X et al. | Science | February 9, 2023
Pleasurable touch is paramount during social behavior, including sexual…
Elias LJ et al. | Cell | February 2, 2023
While there is emerging evidence of sex differences in decision-making behavior…
Cox J et al. | Nature Neuroscience | February 16, 2023
The hypothalamus regulates innate social behaviors, including mating and…
Nair A et al. | Cell | January 11, 2023
Long-range inhibition synchronizes and updates prefrontal task activity
Changes in patterns of activity within the medial prefrontal cortex enable rodents,non-human primates and humans to update their behaviour to adapt to changes in the…
Cho KKA et al. | Nature | May 3, 2023
Control of contextual memory through interneuronal a5-GABAA receptors
γ-Aminobutyric acid type A receptors that incorporate α5 subunits (α5-GABAARs) are highly enriched in the hippocampus and are strongly implicated in control of learning…
Zhu M et al. | PNAS Nexus | April 11, 2023
Identification of an essential spinoparabrachial pathway for mechanical itch
The study identified a specific population of neurons that transmit mechanical itch from the spinal cord to the parabrachial nucleus (PBN) in the brain, and separate…
Ren X et al. | Neuron | April 5, 2023
Oxytocin promotes prefrontal population activity via the PVN-PFC pathway to regulate pain
Liu et al. conducted a study on rats to investigate the neural mechanisms involved in pain processing and modulation. Using behavioral assays and calcium imaging…
Liu Y et al. | Neuron | April 4, 2023
Lateral hypothalamic leptin receptor neurons drive hunger-gated food-seeking and consummatory behaviours in male mice
For survival, it is crucial for eating behaviours to be sequenced through two distinct seeking and consummatory phases. Heterogeneous lateral hypothalamus (LH) neurons…
Lee YH et al. | Nature Communications | March 17, 2023
Complementary lateral hypothalamic populations resist hunger pressure to balance nutritional and social needs
Animals continuously weigh hunger and thirst against competing needs, such as social contact and mating, according to state and opportunity. Yet neuronal mechanisms of…
Petzold A et al. | Cell Metabolism | February 23, 2023