Satb2 neurons in the parabrachial nucleus mediate taste perception
The neural circuitry mediating taste has been mapped out from the periphery to the cortex, but genetic identity of taste-responsive neurons has remained elusive. Here,…
Jarvie BC et al. | Nature Communications | January 11, 2021
Differential encoding in prefrontal cortex projection neuron classes across cognitive tasks
Single-cell transcriptomics has been widely applied to classify neurons in the mammalian brain, while systems neuroscience has historically analyzed the encoding…
Lui JH et al. | Cell | December 17, 2020
Deep imaging in the brainstem reveals functional heterogeneity in V2a neurons controlling locomotion
V2a neurons are a genetically defined cell class that forms a major excitatory descending pathway from the brainstem reticular formation to the spinal cord. Their…
Schwenkgrub J et al. | Science Advances | December 4, 2020
Distinct hypothalamic control of same- and opposite-sex mounting behaviour in mice
Animal behaviours that are superficially similar can express different intents in different contexts, but how this flexibility is achieved at the level of neural…
Karigo T et al. | Nature | December 2, 2020
Parabrachial nucleus circuit governs neuropathic pain-like behavior
The lateral parabrachial nucleus (LPBN) is known to relay noxious information to the amygdala for processing affective responses. However, it is unclear whether the LPBN…
Sun L et al. | Nature Communications | November 25, 2020
The amygdala instructs insular feedback for affective learning
Affective responses depend on assigning value to environmental predictors of threat or reward. Neuroanatomically, this affective value is encoded at both cortical and…
Kargl D et al. | eLife | November 20, 2020