Model-based behavioral control can predict future states based on chosen actions

Akam T et al. | Neuron | November 4, 2020

Functional clusters track parallel processing in direct and indirect pathways

Shin JH et al. | PNAS | October 27, 2020

Mouse fMRI reveals affective computations in a corticolimbic loop

Kargl D et al. | eLife | October 20, 2020

Identification of a key cellular component of sleep homeostasis in mice

Ingiosi AM et al. | Current Biology | September 24, 2020
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Slow neuronal dynamics encode threat responses for emotional memory

Kennedy A et al. | Nature | September 16, 2020
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The amygdala instructs insular feedback for affective learning

Affective responses depend on assigning value to environmental predictors of threat or reward. Neuroanatomically, this affective value is encoded at both cortical and…

Kargl D et al. | eLife | November 20, 2020

Distinct CCK-positive SFO neurons are involved in persistent or transient suppression of water intake

The control of water-intake behavior is critical for life because an excessive water intake induces pathological conditions, such as hyponatremia or water intoxication.…

Matsuda T et al. | Nature Communications | November 10, 2020

The Anterior Cingulate Cortex Predicts Future States to Mediate Model-Based Action Selection

Behavioral control is not unitary. It comprises parallel systems, model based and model free, that respectively generate flexible and habitual behaviors. Model-based…

Akam T et al. | Neuron | November 4, 2020

Spatial organization of functional clusters representing reward and movement information in the striatal direct and indirect pathways

To obtain insights into striatal neural processes underlying reward-based learning and movement control, we examined spatial organizations of striatal neurons related to…

Shin JH et al. | PNAS | October 14, 2020

An Amygdala Circuit Mediates Experience-Dependent Momentary Arrests during Exploration

Exploration of novel environments ensures survival and evolutionary fitness. It is expressed through exploratory bouts and arrests that change dynamically based on…

Botta P et al. | Cell | October 7, 2020

A Role for Astroglial Calcium in Mammalian Sleep and Sleep Regulation

Mammalian sleep expression and regulation have historically been thought to reflect the activity of neurons. Changes in other brain cells (glia) across the sleep-wake…

Ingiosi AM et al. | Current Biology | September 24, 2020
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Modulating D1 rather Yun S et al. | August 3, 2021

Overactive dopamine transmission in psychosis is predicted…

Transient dopamine Mendonça MD et al. | April 20, 2021

Dopamine neurons (DANs) in the substantia nigra pars…

Independent and distinct Manning EE et al. | March 3, 2021

Background Patients with obsessive-compulsive disorder (OCD…

An endogenous opioid Castro DC et al. | February 10, 2021

Mu-opioid peptide receptor (MOPR) stimulation alters…