Model-based behavioral control can predict future states based on chosen actions

Akam T et al. | Neuron | November 4, 2020

Functional clusters track parallel processing in direct and indirect pathways

Shin JH et al. | PNAS | October 27, 2020

Mouse fMRI reveals affective computations in a corticolimbic loop

Kargl D et al. | eLife | October 20, 2020

Identification of a key cellular component of sleep homeostasis in mice

Ingiosi AM et al. | Current Biology | September 24, 2020
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Slow neuronal dynamics encode threat responses for emotional memory

Kennedy A et al. | Nature | September 16, 2020
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An Amygdala Circuit Mediates Experience-Dependent Momentary Arrests during Exploration

Exploration of novel environments ensures survival and evolutionary fitness. It is expressed through exploratory bouts and arrests that change dynamically based on…

Botta P et al. | Cell | October 7, 2020

A Role for Astroglial Calcium in Mammalian Sleep and Sleep Regulation

Mammalian sleep expression and regulation have historically been thought to reflect the activity of neurons. Changes in other brain cells (glia) across the sleep-wake…

Ingiosi AM et al. | Current Biology | September 24, 2020
Research and Publication

Stimulus-specific hypothalamic encoding of a persistent defensive state

Persistent neural activity in cortical, hippocampal, and motor networks has been described as mediating working memory for transiently encountered stimuli. Internal…

Kennedy A et al. | Nature | September 16, 2020
Inscopix Research

Calcium imaging in freely-moving mice during electrical stimulation of deep brain structures

After decades of study in humans and animal models, there remains a lack of consensus regarding how the action of electrical stimulation on neuronal and non-neuronal…

Trevathan JK et al. | Journal of Neural Engineering | September 11, 2020
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Successful In vivo Calcium Imaging with a Head-Mount Miniaturized Microscope in the Amygdala of Freely Behaving Mouse

  In vivo real-time monitoring of neuronal activities in freely moving animals is one of key approaches to link neuronal activity to behavior. For this purpose, an in…

Lee H et al. | Neuroscience | August 26, 2020
Science and Technology

Hindbrain Double-Negative Feedback Mediates Palatability-Guided Food and Water Consumption

Hunger and thirst have distinct goals but control similar ingestive behaviors, and little is known about neural processes that are shared between these behavioral states…

Gong R et al. | Cell | August 24, 2020
Scientific Research

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Modulating D1 rather Yun S et al. | August 3, 2021

Overactive dopamine transmission in psychosis is predicted…

Transient dopamine Mendonça MD et al. | April 20, 2021

Dopamine neurons (DANs) in the substantia nigra pars…

Independent and distinct Manning EE et al. | March 3, 2021

Background Patients with obsessive-compulsive disorder (OCD…

An endogenous opioid Castro DC et al. | February 10, 2021

Mu-opioid peptide receptor (MOPR) stimulation alters…