Parental behaviors secure the well-being of newborns and concomitantly limit negative affective states in adults, which emerge when coping with neonatal distress becomes challenging. Whether negative-affect-related neuronal circuits orchestrate parental actions is unknown. Here…
Lecca S et al. | Neuron | February 1, 2023Transient sexual experiences can have long-lasting effects on behavioral…
ZHOU X et al. | Science | February 9, 2023
Pleasurable touch is paramount during social behavior, including sexual…
Elias LJ et al. | Cell | February 2, 2023
While there is emerging evidence of sex differences in decision-making behavior…
Cox J et al. | Nature Neuroscience | February 16, 2023
The hypothalamus regulates innate social behaviors, including mating and…
Nair A et al. | Cell | January 11, 2023
Efficient and accurate extraction of in vivo calcium signals from microendoscopic video data
In vivo calcium imaging through microendoscopic lenses enables imaging of previously inaccessible neuronal populations deep within the brains of freely moving animals.…
Zhou P et al. | eLife | February 22, 2018
A Hypothalamic Switch for REM and Non-REM Sleep
Rapid eye movement (REM) and non-REM (NREM) sleep are controlled by specific neuronal circuits. Here we show that galanin-expressing GABAergic neurons in the dorsomedial…
Chen K et al. | Neuron | February 22, 2018
Genetically encoded calcium indicator with NTnC-like design and enhanced fluorescence contrast and kinetics
We demonstrate that expanding the family of NTnC-like calcium indicators is a promising strategy for the development of the next generation of GECIs with smaller…
Doronin DA et al. | BMC Biotechnology | February 13, 2018
Fast-Spiking Interneurons Supply Feedforward Control of Bursting, Calcium, and Plasticity for Efficient Learning
Fast-spiking interneurons (FSIs) are a prominent class of forebrain GABAergic cells implicated in two seemingly independent network functions: gain control and network…
Owen SF et al. | Cell | February 8, 2018
Dopamine neuron activity before action initiation gates and invigorates future movements
Deciding when and whether to move is critical for survival. Loss of dopamine neurons (DANs) of the substantia nigra pars compacta (SNc) in patients with Parkinson’s…
Silva JAd et al. | Nature | January 31, 2018
Anxiety Cells in a Hippocampal-Hypothalamic Circuit
The hippocampus is traditionally thought to transmit contextual information to limbic structures where it acquires valence. Using freely moving calcium imaging and…
Jimenez JC et al. | Neuron | January 31, 2018