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News and commentary from the Inscopix community Preclinical Drug Development
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Parkinson’s disease (PD) is a neurological disorder that affects 6 hundred thousand to more than 1 million people in the United States, or over 6 million worldwide, making it the second most prevalent brain disease behind Alzheimer’s. This disease presents differently in every individual but is typically marked by motor symptoms such as resting tremors,

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From behavioral studies on learning and memory to sleep-wakefulness, 2023 was a year full of researchers uncovering…

Melissa Martin

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Image: Data courtesy of Jones Parker lab – Northwestern University. Efforts to develop more effective drugs for treating…

Jonathan Zapata

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Pregnancy and childbirth are extraordinary experiences that profoundly change a mother’s life. But did you know that the…

Yasaman Farshchi

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Since this is my first blog post, I think a brief introduction is in order! I am currently the Director of Translational Science at Inscopix, overseeing our scientific programs with a translational and preclinical focus – which includes such activities as product and application development and scientific partnerships with academic and pharma/biotech groups. Before joining

Jonathan Nassi

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Believe it or not, this post was on our editorial calendar way back in January, and not even in our wildest imagination had we envisioned that at the time of publishing, life itself would become defined by the topic at hand- fear. Fear and anxiety are all too familiar to the world as a whole

Sushmitha Gururaj

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We’re two months into 2020 and our beloved circuit neuroscience community has already served up so many treats that we’re wondering if it’s still the holidays! We’re excited to share with you our collection of top reads circuit neuroscience papers of 2020 thus far. You’ll find that each of them informs on fundamental biological functions

Sushmitha Gururaj

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Our brain’s ability to respond and adapt to stress is imperative to health, with dysfunctional neuroadaptation being a key trigger for development and exacerbation of a variety of neuropsychiatric disorders like depression, post-traumatic stress disorder (PTSD) and addiction. Endogenous cannabinoids (eCBs) are well established regulators of this stress response, making their sophisticated synaptic signaling mechanisms

Sushmitha Gururaj

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Our social skills pervade most aspects our life, defining our role in the family, workplace, society and beyond. People affected by Autism Spectrum Disorders (ASD) face challenges in social interaction and communication, experiencing core symptoms such as repetitive behaviors and restricted interests. The lab of Rui Costa at Columbia University explores the neurobiology of ‘self-paced’

Sushmitha Gururaj

Each year, more than 30,000 brain researchers come together at the Society for Neuroscience (SfN) annual meeting to present their latest research. 2012 was our first year at SfN, where we launched our very first product-–nVistaᵀᴹ–-a miniature microscope-based system to map brain circuit activity at single-cell resolution in thousands of neurons in naturally behaving rodents.

Kunal Ghosh

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