Inscopix’s nVoke product for simultaneous imaging and optogenetics empowers researchers to dissect how different groups of neurons, whether intermixed in microcircuits or separated across brain regions, exert directional and causal influence on each other to shape the computations that underlie cognition and behavior.
The basal ganglia
nVoke has made it possible for us to measure how optogenetic inhibition alters multineuronal patterns of activity in freely behaving mice. This is leading us to a previously unattainable understanding of the links between the activity of a specific subtype of mPFC neurons, multineuronal patterns of activity, and behavior.
- Vikaas Sohal, PhD, UCSF