Deconstruction of Vermal Cerebellum in Ramp Locomotion in Mice
The cerebellum is involved in encoding balance, posture, speed, and gravity during locomotion. However, most studies are carried out on flat surfaces, and little is…
Lyu C et al. | Advanced Science | November 14, 2022Analyzing the brainstem circuits for respiratory chemosensitivity in freely moving mice
Regulation of systemic PCO2 is a life-preserving homeostatic mechanism. In the medulla oblongata, the retrotrapezoid nucleus (RTN) and rostral medullary Raphe are…
Bhandare A et al. | eLife | October 27, 2022Nigrostriatal dopamine pathway regulates auditory discrimination behavior
The auditory striatum, the tail portion of dorsal striatum in basal ganglia, is implicated in perceptual decision-making, transforming auditory stimuli to action…
Chen APF et al. | Nature Communications | October 7, 2022
Longitudinal Monitoring of Prefrontal Cortical Ensemble Dynamics Reveals New Insights into Stress Habituation
The prefrontal cortex is highly susceptible to the detrimental effects of stress and has been implicated in the pathogenesis of stress-related psychiatric disorders. It…
Patel S et al. | Neurobiology of Stress | September 3, 2022
Fiber photometry in striatum reflects primarily nonsomatic changes in calcium
Fiber photometry enables recording of population neuronal calcium dynamics in awake mice. While the popularity of fiber photometry has grown in recent years, it remains…
Legaria AA et al. | Nature Neuroscience | August 30, 2022A central alarm system that gates multi-sensory innate threat cues to the amygdala
Perception of threats is essential for survival. Previous findings suggest that parallel pathways independently relay innate threat signals from different sensory…
Kang SJ et al. | Cell Reports | August 16, 2022