Parental behaviors secure the well-being of newborns and concomitantly limit negative affective states in adults, which emerge when coping with neonatal distress becomes challenging. Whether negative-affect-related neuronal circuits orchestrate parental actions is unknown. Here…

Lecca S et al. | Neuron | February 1, 2023

Transient sexual experiences can have long-lasting effects on behavioral…

ZHOU X et al. | Science | February 9, 2023

Pleasurable touch is paramount during social behavior, including sexual…

Elias LJ et al. | Cell | February 2, 2023

While there is emerging evidence of sex differences in decision-making behavior…

Cox J et al. | Nature Neuroscience | February 16, 2023

The hypothalamus regulates innate social behaviors, including mating and…

Nair A et al. | Cell | January 11, 2023
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Nigrostriatal dopamine pathway regulates auditory discrimination behavior

The auditory striatum, the tail portion of dorsal striatum in basal ganglia, is implicated in perceptual decision-making, transforming auditory stimuli to action…

Chen APF et al. | Nature Communications | October 8, 2022

Fiber photometry in striatum reflects primarily nonsomatic changes in calcium

Fiber photometry enables recording of population neuronal calcium dynamics in awake mice. While the popularity of fiber photometry has grown in recent years, it remains…

Legaria AA et al. | Nature Neuroscience | August 30, 2022

A central alarm system that gates multi-sensory innate threat cues to the amygdala

Perception of threats is essential for survival. Previous findings suggest that parallel pathways independently relay innate threat signals from different sensory…

Kang SJ et al. | Cell Reports | August 16, 2022

Dose-dependent suppression of hippocampal contextual memory formation, place cells, and spatial engrams by the NMDAR antagonist (R)-CPP

We recently reported that the competitive NMDAR antagonist (R,S)-3-(2-carboxypiperazin-4-yl)-propyl-1-phosphonic acid (CPP) does not suppress NMDAR-mediated field EPSPs…

Zhu M et al. | Neuropharmacology | August 14, 2022

Control of non-REM sleep by ventrolateral medulla glutamatergic neurons projecting to the preoptic area

Understanding the neural mechanisms underlying sleep state transitions is a fundamental goal of neurobiology and important for the development of new treatments for…

Teng S et al. | Nature Communications | August 12, 2022

A molecularly defined D1 medium spiny neuron subtype negatively regulates cocaine addiction

The  striatum  plays  a  critical  role  in  regulating  addiction-related  behaviors.  The  conventional  dichotomy  model  suggests  that  striatal  D1/D2  medium  …

Zhao Z et al. | Science Advances | August 12, 2022

bioRxiv Wire

Lateral parabrachial Kaur I et al. | May 5, 2023

Although CGRP neurons in the external lateral parabrachial…

Sex differences in Murugan I et al. | March 10, 2023

The reinforcing nature of social interactions is necessary…

Serotonin in the Hyun I et al. | March 9, 2023

Cognitive flexibility is the ability of the brain to switch…

An approximate line Nair A et al. | June 2, 2022

The hypothalamus plays a key role in regulating innate…