Nigrostriatal dopamine pathway regulates auditory discrimination behavior
The auditory striatum, the tail portion of dorsal striatum in basal ganglia, is implicated in perceptual decision-making, transforming auditory stimuli to action…
Chen APF et al. | Nature Communications | October 8, 2022
Fiber photometry in striatum reflects primarily nonsomatic changes in calcium
Fiber photometry enables recording of population neuronal calcium dynamics in awake mice. While the popularity of fiber photometry has grown in recent years, it remains…
Legaria AA et al. | Nature Neuroscience | August 30, 2022A central alarm system that gates multi-sensory innate threat cues to the amygdala
Perception of threats is essential for survival. Previous findings suggest that parallel pathways independently relay innate threat signals from different sensory…
Kang SJ et al. | Cell Reports | August 16, 2022Dose-dependent suppression of hippocampal contextual memory formation, place cells, and spatial engrams by the NMDAR antagonist (R)-CPP
We recently reported that the competitive NMDAR antagonist (R,S)-3-(2-carboxypiperazin-4-yl)-propyl-1-phosphonic acid (CPP) does not suppress NMDAR-mediated field EPSPs…
Zhu M et al. | Neuropharmacology | August 14, 2022Control of non-REM sleep by ventrolateral medulla glutamatergic neurons projecting to the preoptic area
Understanding the neural mechanisms underlying sleep state transitions is a fundamental goal of neurobiology and important for the development of new treatments for…
Teng S et al. | Nature Communications | August 12, 2022A molecularly defined D1 medium spiny neuron subtype negatively regulates cocaine addiction
The striatum plays a critical role in regulating addiction-related behaviors. The conventional dichotomy model suggests that striatal D1/D2 medium …
Zhao Z et al. | Science Advances | August 12, 2022