Bias-free estimation of information content in temporally sparse neuronal activity
Applying information theoretic measures to neuronal activity data enables the quantification of neuronal encoding quality. However, when the sample size is limited, a…
Sheintuch L et al. | PLOS Computational Biology | February 11, 2022Hippocampal-amygdala memory circuits govern experience-dependent observational fear
The empathic ability to vicariously experience the other’s fearful situation, a process called observational fear (OF), is critical to survive in nature and function in…
Terranova JI et al. | Neuron | February 8, 2022
In vivo imaging of the GnRH pulse generator reveals a temporal order of neuronal activation and synchronization during each pulse
A hypothalamic pulse generator located in the arcuate nucleus controls episodic release of gonadotropin-releasing hormone (GnRH) and luteinizing hormone (LH) and is…
Moore AM et al. | PNAS | February 8, 2022
Targeted activation of midbrain neurons restores locomotor function in mouse models of parkinsonism
The pedunculopontine nucleus (PPN) is a locomotor command area containing glutamatergic neurons that control locomotor initiation and maintenance. These motor actions…
Masini D et al. | Nature Communications | January 26, 2022
A neuronal mechanism for motivational control of behavior
Acting to achieve goals depends on the ability to motivate specific behaviors based on their predicted consequences given an individual’s internal state. However, the…
Courtin J et al. | Science | January 7, 2022
Divergent brainstem opioidergic pathways that coordinate breathing with pain and emotions
Breathing can be heavily influenced by pain or internal emotional states, but the neural circuitry underlying this tight coordination is unknown. Here we report that …
Liu S et al. | Neuron | December 17, 2021