Parental behaviors secure the well-being of newborns and concomitantly limit negative affective states in adults, which emerge when coping with neonatal distress becomes challenging. Whether negative-affect-related neuronal circuits orchestrate parental actions is unknown. Here…
Lecca S et al. | Neuron | February 1, 2023Transient sexual experiences can have long-lasting effects on behavioral…
ZHOU X et al. | Science | February 9, 2023
Pleasurable touch is paramount during social behavior, including sexual…
Elias LJ et al. | Cell | February 2, 2023
While there is emerging evidence of sex differences in decision-making behavior…
Cox J et al. | Nature Neuroscience | February 16, 2023
The hypothalamus regulates innate social behaviors, including mating and…
Nair A et al. | Cell | January 11, 2023
A weakened recurrent circuit in the hippocampus of Rett syndrome mice disrupts long-term memory representations
Successful recall of a contextual memory requires reactivating ensembles of hippocampal cells that were allocated during memory formation. Altering the ratio of…
He L et al. | Neuron | May 18, 2022
Choice-selective sequences dominate in cortical relative to thalamic inputs to NAc to support reinforcement learning
How are actions linked with subsequent outcomes to guide choices? The nucleus accumbens, which is implicated in this process, receives glutamatergic inputs from the…
Parker NF et al. | Cell Reports | May 17, 2022
The impact of pitolisant, an H3 receptor antagonist/inverse agonist, on perirhinal cortex activity in individual neuron and neuronal population levels
Histamine is a neurotransmitter that modulates neuronal activity and regulates various brain functions. Histamine H3 receptor (H3R) antagonists/inverse agonists enhance…
Hirano K et al. | Scientific Reports | May 12, 2022
Top-down control of hippocampal signal-to-noise by prefrontal long-range inhibition
Prefrontal cortex (PFC) is postulated to exert “top-down control” on information processing throughout the brain to promote specific behaviors. However, pathways…
Malik R et al. | Cell | April 28, 2022
Encoding of environmental cues in central amygdala neurons during foraging
To successfully forage in an environment filled with rewards and threats, animals need to rely on familiar structures of their environment that signal food availability…
Ponserre M et al. | The Journal of Neuroscience | April 5, 2022
A dentate gyrus-CA3 inhibitory circuit promotes evolution of hippocampal-cortical ensembles during memory consolidation
Memories encoded in the dentate gyrus (DG) ‒ CA3 circuit of the hippocampus are routed from CA1 to anterior cingulate cortex (ACC) for consolidation. Although CA1…
Twarkowski H et al. | eLife | February 22, 2022