Deep imaging in the brainstem reveals functional heterogeneity in V2a neurons controlling locomotion
V2a neurons are a genetically defined cell class that forms a major excitatory descending pathway from the brainstem reticular formation to the spinal cord. Their…
Schwenkgrub J et al. | Science Advances | December 4, 2020
Distinct hypothalamic control of same- and opposite-sex mounting behaviour in mice
Animal behaviours that are superficially similar can express different intents in different contexts, but how this flexibility is achieved at the level of neural…
Karigo T et al. | Nature | December 2, 2020
Parabrachial nucleus circuit governs neuropathic pain-like behavior
The lateral parabrachial nucleus (LPBN) is known to relay noxious information to the amygdala for processing affective responses. However, it is unclear whether the LPBN…
Sun L et al. | Nature Communications | November 25, 2020
The amygdala instructs insular feedback for affective learning
Affective responses depend on assigning value to environmental predictors of threat or reward. Neuroanatomically, this affective value is encoded at both cortical and…
Kargl D et al. | eLife | November 20, 2020
Distinct CCK-positive SFO neurons are involved in persistent or transient suppression of water intake
The control of water-intake behavior is critical for life because an excessive water intake induces pathological conditions, such as hyponatremia or water intoxication.…
Matsuda T et al. | Nature Communications | November 10, 2020
The Anterior Cingulate Cortex Predicts Future States to Mediate Model-Based Action Selection
Behavioral control is not unitary. It comprises parallel systems, model based and model free, that respectively generate flexible and habitual behaviors. Model-based…
Akam T et al. | Neuron | November 4, 2020