Distinct hippocampal pathways mediate dissociable roles of context in memory retrieval
Memories about sensory experiences are tightly linked to the context in which they were formed. Memory contextualization is fundamental for the selection of appropriate…
Xu C et al. | Cell | October 20, 2016
Circuit-based interrogation of sleep control
Sleep is a fundamental biological process observed widely in the animal kingdom, but the neural circuits generating sleep remain poorly understood. Understanding the…
Weber F et al. | Nature | October 5, 2016
Ventral CA1 neurons store social memory
The medial temporal lobe, including the hippocampus, has been implicated in social memory. However, it remains unknown which parts of these brain regions and their…
Okuyama T et al. | Science | September 30, 2016
A new design for a green calcium indicator with a smaller size and a reduced number of calcium-binding sites
Genetically encoded calcium indicators (GECIs) are mainly represented by two- or one-fluorophore-based sensors. One type of two-fluorophore-based sensor, carrying …
Barykina NV et al. | Scientific Reports | September 28, 2016
Decreasing striatopallidal pathway function enhances motivation by energizing the initiation of goal-directed action
Altered dopamine D2 receptor (D2R) binding in the striatum has been associated with abnormal motivation in neuropsychiatric disorders, including schizophrenia. Here, we…
Poyraz FC et al. | The Journal of Neuroscience | June 1, 2016
Calcium imaging of basal forebrain activity during innate and learned behavio
The basal forebrain (BF) plays crucial roles in arousal, attention, and memory, and its impairment is associated with a variety of cognitive deficits. The BF consists of…
Harrison TC et al. | Frontiers in Neural Circuits | May 9, 2016