CRF in BNST influences pain experience and behavior in a gender specific manner

Yu W et al. | Scientific Reports | June 14, 2021

LoTRA- a versatile algorithm for analyzing time-series data

Chomiak T et al. | NPJ Parkinson's Disease | November 9, 2021

DGCs' activity predicts auditory decisions after task learning

Shen J et al. | Scientific Reports | July 13, 2021

lVTA Vgat and Vglut2 projections onto dmCINs influence aversive stimuli…

Rizzi G et al. | Cell Reports | March 16, 2021

 Genetic identity of taste perceiving neurons

Jarvie BC et al. | Nature Communications | January 11, 2021
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Miniature microscopes for manipulating and recording in vivo brain activity

Here we describe the development and application of miniature integrated microscopes (miniscopes) paired with microendoscopes that allow for the visualization and…

Stamatakis AM et al. | Microscopy | August 2, 2021

Complete representation of action space and value in all dorsal striatal pathways

The dorsal striatum plays a central role in the selection, execution, and evaluation of actions. An emerging model attributes action selection to the matrix and…

Weglage M et al. | Cell Reports | July 27, 2021
Cell Reports

Reverse optogenetics of G protein signaling by zebrafish non-visual opsin Opn7b for synchronization of neuronal networks

Opn7b is a non-visual G protein-coupled receptor expressed in zebrafish. Here we find that Opn7b expressed in HEK cells constitutively activates the Gi/o pathway and…

Karapinar R et al. | Nature Communications | July 23, 2021
Nature Communications

Dichotomous dopaminergic and noradrenergic neural states mediate distinct aspects of exploitative behavioral states

The balance between exploiting known actions and exploring alternatives is critical for survival and hypothesized to rely on shifts in neuromodulation. We developed a…

Koralek AC et al. | Science Advances | July 23, 2021
Science Advances

Dentate granule cells encode auditory decisions after reinforcement learning in rats

Auditory-cued goal-oriented behaviors requires the participation of cortical and subcortical brain areas, but how neural circuits associate sensory-based decisions with…

Shen J et al. | Scientific Reports | July 13, 2021
Scientific Reports

Application of optogenetics and in vivo imaging approaches for elucidating the neurobiology of addiction

The neurobiology of addiction has been an intense topic of investigation for more than 50 years. Over this time, technological innovation in methods for studying brain…

Vickstrom CR et al. | Molecular Psychiatry | June 18, 2021

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Modulating D1 rather Yun S et al. | August 3, 2021

Overactive dopamine transmission in psychosis is predicted…

Transient dopamine Mendonça MD et al. | April 20, 2021

Dopamine neurons (DANs) in the substantia nigra pars…

Independent and distinct Manning EE et al. | March 3, 2021

Background Patients with obsessive-compulsive disorder (OCD…

An endogenous opioid Castro DC et al. | February 10, 2021

Mu-opioid peptide receptor (MOPR) stimulation alters…