CRF in BNST influences pain experience and behavior in a gender specific manner
Yu W et al. | Scientific Reports | June 14, 2021LoTRA- a versatile algorithm for analyzing time-series data
Chomiak T et al. | NPJ Parkinson's Disease | November 9, 2021
DGCs' activity predicts auditory decisions after task learning
Shen J et al. | Scientific Reports | July 13, 2021
lVTA Vgat and Vglut2 projections onto dmCINs influence aversive stimuli…
Rizzi G et al. | Cell Reports | March 16, 2021
Genetic identity of taste perceiving neurons
Jarvie BC et al. | Nature Communications | January 11, 2021
Divergent medial amygdala projections regulate approach–avoidance conflict behavior
Avoidance of innate threats is often in conflict with motivations to engage in exploratory approach behavior. The neural pathways that mediate this approach–avoidance…
Miller SM et al. | Nature Neuroscience | February 25, 2019
A hypothalamus-habenula circuit controls aversion
Encoding and predicting aversive events are critical functions of circuits that support survival and emotional well-being. Maladaptive circuit changes in emotional…
Lazaridis I et al. | Molecular Psychiatry | February 12, 2019
Unsupervised discovery of temporal sequences in high-dimensional datasets, with applications to neuroscience
Identifying low-dimensional features that describe large-scale neural recordings is a major challenge in neuroscience. Repeated temporal patterns (sequences) are thought…
Mackevicius EL et al. | eLife | February 5, 2019
Dorsolateral septum somatostatin interneurons gate mobility to calibrate context-specific behavioral fear responses
Adaptive fear responses to external threats rely upon efficient relay of computations underlying contextual encoding to subcortical circuits. Brain-wide analysis of…
Besnard A et al. | Nature Neuroscience | February 4, 2019
Leveraging calcium imaging to illuminate circuit dysfunction in addiction
Alcohol and drug use can dysregulate neural circuit function to produce a wide range of neuropsychiatric disorders, including addiction. To understand the neural circuit…
Siciliano CA et al. | Alcohol | February 1, 2019
Intense threat switches dorsal raphe serotonin neurons to a paradoxical operational mode
Survival depends on the selection of behaviors adaptive for the current environment. For example, a mouse should run from a rapidly looming hawk but should freeze if the…
Seo C et al. | Science | January 31, 2019