Model-based behavioral control can predict future states based on chosen actions
Akam T et al. | Neuron | November 4, 2020Functional clusters track parallel processing in direct and indirect pathways
Shin JH et al. | PNAS | October 27, 2020
Mouse fMRI reveals affective computations in a corticolimbic loop
Kargl D et al. | eLife | October 20, 2020
Identification of a key cellular component of sleep homeostasis in mice
Ingiosi AM et al. | Current Biology | September 24, 2020
Slow neuronal dynamics encode threat responses for emotional memory
Kennedy A et al. | Nature | September 16, 2020
Persistent Activation of Central Amygdala CRF Neurons Helps Drive the Immediate Fear Extinction Deficit
Fear extinction is an active learning process whereby previously established conditioned responses to a conditioned stimulus are suppressed. Paradoxically, when…
Jo YS et al. | Nature Communications | January 22, 2020
Generality and opponency of rostromedial tegmental (RMTg) roles in valence processing
The rostromedial tegmental nucleus (RMTg), a GABAergic afferent to midbrain dopamine (DA) neurons, has been hypothesized to be broadly activated by aversive stimuli.…
Li H et al. | eLife | January 22, 2020
Pcdhβ deficiency affects hippocampal CA1 ensemble activity and contextual fear discrimination
Clustered protocadherins (Pcdhs), a large group of adhesion molecules, are important for axonal projections and dendritic spread, but little is known about how they…
Asai H et al. | Molecular Brain | January 20, 2020
Opposing Somatic and Dendritic Expression of Stimulus-Selective Response Plasticity in Mouse Primary Visual Cortex
Daily exposure of awake mice to a phase-reversing visual grating stimulus leads to enhancement of the visual-evoked potential (VEP) in layer 4 of the primary visual…
Kim T et al. | Frontiers in Cellular Neuroscience | January 14, 2020
Amygdala Reward Neurons Form and Store Fear Extinction Memory
The ability to extinguish conditioned fear memory is critical for adaptive control of fear response, and its impairment is a hallmark of emotional disorders like post-…
Zhang X et al. | Neuron | January 14, 2020
Endocannabinoid Signaling Collapse Mediates Stress-Induced Amygdalo-Cortical Strengthening
Functional coupling between the amygdala and the dorsomedial prefrontal cortex (dmPFC) has been implicated in the generation of negative affective states; however, the…
Marcus DJ et al. | Neuron | January 13, 2020