Model-based behavioral control can predict future states based on chosen actions

Akam T et al. | Neuron | November 4, 2020

Functional clusters track parallel processing in direct and indirect pathways

Shin JH et al. | PNAS | October 27, 2020

Mouse fMRI reveals affective computations in a corticolimbic loop

Kargl D et al. | eLife | October 20, 2020

Identification of a key cellular component of sleep homeostasis in mice

Ingiosi AM et al. | Current Biology | September 24, 2020
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Slow neuronal dynamics encode threat responses for emotional memory

Kennedy A et al. | Nature | September 16, 2020
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Imaging the Neural Circuit Basis of Social Behavior: Insights from Mouse and Human Studies

Social behavior includes a variety of behaviors that are expressed between two or more individuals. In humans, impairment of social function (i.e., social behavior and…

MIURA I et al. | Neurologia medico-chirurgica | August 1, 2020

REM sleep stabilizes hypothalamic representation of feeding behavior

During rapid eye movement (REM) sleep, behavioral unresponsiveness contrasts strongly with intense brain-wide neural network dynamics. Yet, the physiological functions…

Oesch LT et al. | PNAS | July 30, 2020

Dysregulation of the Synaptic Cytoskeleton in the PFC Drives Neural Circuit Pathology, Leading to Social Dysfunction

Psychiatric disorders are highly heritable pathologies of altered neural circuit functioning. How genetic mutations lead to specific neural circuit abnormalities…

Kim IH et al. | Cell Reports | July 28, 2020

Contextual fear memory retrieval by correlated ensembles of ventral CA1 neurons

Ventral hippocampal CA1 (vCA1) projections to the amygdala are necessary for contextual fear memory. Here we used in vivo Ca2+ imaging in mice to assess the temporal…

Jimenez JC et al. | Nature Communications | July 13, 2020

Precision Calcium Imaging of Dense Neural Populations via a Cell-Body-Targeted Calcium Indicator

Methods for one-photon fluorescent imaging of calcium dynamics can capture the activity of hundreds of neurons across large fields of view at a low equipment complexity…

Shemesh OA et al. | Neuron | June 26, 2020

Soma-Targeted Imaging of Neural Circuits by Ribosome Tethering

Neuroscience relies on techniques for imaging the structure and dynamics of neural circuits, but the cell bodies of individual neurons are often obscured by overlapping…

Chen Y et al. | Neuron | June 22, 2020

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Modulating D1 rather Yun S et al. | August 3, 2021

Overactive dopamine transmission in psychosis is predicted…

Transient dopamine Mendonça MD et al. | April 20, 2021

Dopamine neurons (DANs) in the substantia nigra pars…

Independent and distinct Manning EE et al. | March 3, 2021

Background Patients with obsessive-compulsive disorder (OCD…

An endogenous opioid Castro DC et al. | February 10, 2021

Mu-opioid peptide receptor (MOPR) stimulation alters…