Disrupted population coding in the prefrontal cortex underlies pain aversion
The prefrontal cortex (PFC) regulates a wide range of sensory experiences. Chronic pain is known to impair normal neural response, leading to enhanced aversion. However…
Li A et al. | Cell Reports | November 9, 2021
A versatile computational algorithm for time-series data analysis and machine-learning models
Here we introduce Local Topological Recurrence Analysis (LoTRA), a simple computational approach for analyzing time-series data. Its versatility is elucidated using…
Chomiak T et al. | npj Parkinson's Disease | November 9, 2021
Olfactory landmarks and path integration converge to form a cognitive spatial map
The convergence of internal path integration and external sensory landmarks generates a cognitive spatial map in the hippocampus. We studied how localized odor cues are…
Fischler-Ruiz W et al. | Neuron | October 27, 2021
Neural dynamics underlying birdsong practice and performance
Musical and athletic skills are learned and maintained through intensive practice to enable precise and reliable performance for an audience. Consequently, understanding…
Alvarado JS et al. | Nature | October 20, 2021
An endogenous opioid circuit determines state-dependent reward consumption
µ-Opioid peptide receptor (MOPR) stimulation alters respiration, analgesia and reward behaviour, and can induce substance abuse and overdose1,2,3. Despite its evident…
Castro DC et al. | Nature | October 13, 2021
Dynamic dichotomy of accumbal population activity underlies cocaine sensitization
Locomotor sensitization (LS) is an early behavioral adaptation to addictive drugs, driven by the increase of dopamine in the Nucleus Accumbens (NAc). However, the effect…
Zessen Rv et al. | eLife | October 5, 2021