Parental behaviors secure the well-being of newborns and concomitantly limit negative affective states in adults, which emerge when coping with neonatal distress becomes challenging. Whether negative-affect-related neuronal circuits orchestrate parental actions is unknown. Here…
Lecca S et al. | Neuron | February 1, 2023Transient sexual experiences can have long-lasting effects on behavioral…
ZHOU X et al. | Science | February 8, 2023
Pleasurable touch is paramount during social behavior, including sexual…
Elias LJ et al. | Cell | February 2, 2023
While there is emerging evidence of sex differences in decision-making behavior…
Cox J et al. | Nature Neuroscience | February 16, 2023
The hypothalamus regulates innate social behaviors, including mating and…
Nair A et al. | Cell | January 10, 2023
CaV3.1 T-type calcium channels are important for spatial memory processing in the dorsal subiculum
The dorsal subiculum (dSub) is one of the key structures responsible for the formation of hippocampal memory traces but the contribution of individual ionic currents to…
Joksimovic SM et al. | Neuropharmacology | December 28, 2022
Disruption of hippocampal neuronal circuit function depends upon behavioral state in the APP/PS1 mouse model of Alzheimer’s disease
The Alzheimer's disease-associated peptide amyloid-beta (Aβ) has been associated with neuronal hyperactivity under anesthesia, but clinical trials of anticonvulsants or…
Zhou H et al. | Scientific Reports | December 5, 2022
Hippocampal representations of foraging trajectories depend upon spatial context
Animals learn trajectories to rewards in both spatial, navigational contexts and relational, non-navigational contexts. Synchronous reactivation of hippocampal activity…
Jiang W et al. | Nature Neuroscience | November 28, 2022
Forebrain Glucocorticoid Receptor Overexpression Alters Behavioral Encoding of Hippocampal CA1 Pyramidal Cells In Mice
Glucocorticoid signaling influences hippocampal-dependent behavior and vulnerability to stress-related neuropsychiatric disorders. In mice, lifelong overexpression of…
Gavade S et al. | eNeuro | November 22, 2022
Exercise increases information content and affects long-term stability of hippocampal place codes
Physical exercise is known to augment brain functioning, improving memory and cognition. However, while some of the physiological effects of physical activity on the…
Rechavi Y et al. | Cell Reports | November 22, 2022
Tripartite extended amygdala–basal ganglia CRH circuit drives locomotor activation and avoidance behavior
An adaptive stress response involves various mediators and circuits orchestrating a complex interplay of physiological, emotional, and behavioral adjustments. We…
Chang S et al. | Science Advances | November 16, 2022