Parental behaviors secure the well-being of newborns and concomitantly limit negative affective states in adults, which emerge when coping with neonatal distress becomes challenging. Whether negative-affect-related neuronal circuits orchestrate parental actions is unknown. Here…

Lecca S et al. | Neuron | February 1, 2023

Transient sexual experiences can have long-lasting effects on behavioral…

ZHOU X et al. | Science | February 8, 2023

Pleasurable touch is paramount during social behavior, including sexual…

Elias LJ et al. | Cell | February 2, 2023

While there is emerging evidence of sex differences in decision-making behavior…

Cox J et al. | Nature Neuroscience | February 16, 2023

The hypothalamus regulates innate social behaviors, including mating and…

Nair A et al. | Cell | January 10, 2023
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CaV3.1 T-type calcium channels are important for spatial memory processing in the dorsal subiculum

The dorsal subiculum (dSub) is one of the key structures responsible for the formation of hippocampal memory traces but the contribution of individual ionic currents to…

Joksimovic SM et al. | Neuropharmacology | December 28, 2022

Disruption of hippocampal neuronal circuit function depends upon behavioral state in the APP/PS1 mouse model of Alzheimer’s disease

The Alzheimer's disease-associated peptide amyloid-beta (Aβ) has been associated with neuronal hyperactivity under anesthesia, but clinical trials of anticonvulsants or…

Zhou H et al. | Scientific Reports | December 5, 2022

Hippocampal representations of foraging trajectories depend upon spatial context

Animals learn trajectories to rewards in both spatial, navigational contexts and relational, non-navigational contexts. Synchronous reactivation of hippocampal activity…

Jiang W et al. | Nature Neuroscience | November 28, 2022

Forebrain Glucocorticoid Receptor Overexpression Alters Behavioral Encoding of Hippocampal CA1 Pyramidal Cells In Mice

Glucocorticoid signaling influences hippocampal-dependent behavior and vulnerability to stress-related neuropsychiatric disorders. In mice, lifelong overexpression of…

Gavade S et al. | eNeuro | November 22, 2022

Exercise increases information content and affects long-term stability of hippocampal place codes

Physical exercise is known to augment brain functioning, improving memory and cognition. However, while some of the physiological effects of physical activity on the…

Rechavi Y et al. | Cell Reports | November 22, 2022
Cell Reports

Tripartite extended amygdala–basal ganglia CRH circuit drives locomotor activation and avoidance behavior

An adaptive stress response involves various mediators and circuits orchestrating a complex interplay of physiological, emotional, and behavioral adjustments. We…

Chang S et al. | Science Advances | November 16, 2022
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Advances in optical imaging approaches and fluorescent…

Lateral parabrachial Kaur I et al. | May 5, 2023

Although CGRP neurons in the external lateral parabrachial…

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The reinforcing nature of social interactions is necessary…

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Cognitive flexibility is the ability of the brain to switch…