Model-based behavioral control can predict future states based on chosen actions

Akam T et al. | Neuron | November 4, 2020

Functional clusters track parallel processing in direct and indirect pathways

Shin JH et al. | PNAS | October 27, 2020

Mouse fMRI reveals affective computations in a corticolimbic loop

Kargl D et al. | eLife | October 20, 2020

Identification of a key cellular component of sleep homeostasis in mice

Ingiosi AM et al. | Current Biology | September 24, 2020
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Slow neuronal dynamics encode threat responses for emotional memory

Kennedy A et al. | Nature | September 16, 2020
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Distinct hypothalamic control of same- and opposite-sex mounting behaviour in mice

Animal behaviours that are superficially similar can express different intents in different contexts, but how this flexibility is achieved at the level of neural…

Karigo T et al. | Nature | December 2, 2020

Parabrachial nucleus circuit governs neuropathic pain-like behavior

The lateral parabrachial nucleus (LPBN) is known to relay noxious information to the amygdala for processing affective responses. However, it is unclear whether the LPBN…

Sun L et al. | Nature Communications | November 25, 2020

The amygdala instructs insular feedback for affective learning

Affective responses depend on assigning value to environmental predictors of threat or reward. Neuroanatomically, this affective value is encoded at both cortical and…

Kargl D et al. | eLife | November 20, 2020

Distinct CCK-positive SFO neurons are involved in persistent or transient suppression of water intake

The control of water-intake behavior is critical for life because an excessive water intake induces pathological conditions, such as hyponatremia or water intoxication.…

Matsuda T et al. | Nature Communications | November 10, 2020

The Anterior Cingulate Cortex Predicts Future States to Mediate Model-Based Action Selection

Behavioral control is not unitary. It comprises parallel systems, model based and model free, that respectively generate flexible and habitual behaviors. Model-based…

Akam T et al. | Neuron | November 4, 2020

Spatial organization of functional clusters representing reward and movement information in the striatal direct and indirect pathways

To obtain insights into striatal neural processes underlying reward-based learning and movement control, we examined spatial organizations of striatal neurons related to…

Shin JH et al. | PNAS | October 14, 2020

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Modulating D1 rather Yun S et al. | August 3, 2021

Overactive dopamine transmission in psychosis is predicted…

Transient dopamine Mendonça MD et al. | April 20, 2021

Dopamine neurons (DANs) in the substantia nigra pars…

Independent and distinct Manning EE et al. | March 3, 2021

Background Patients with obsessive-compulsive disorder (OCD…

An endogenous opioid Castro DC et al. | February 10, 2021

Mu-opioid peptide receptor (MOPR) stimulation alters…