The Spatiotemporal Organization of the Striatum Encodes Action Space
Activity in striatal direct- and indirect-pathway spiny projection neurons (SPNs) is critical for proper movement. However, little is known about the spatiotemporal…
Klaus A et al. | Neuron | August 30, 2017
Central amygdala circuits modulate food consumption through a positive-valence mechanism
The complex behaviors underlying reward seeking and consumption are integral to organism survival. The hypothalamus and mesolimbic dopamine system are key mediators of…
Douglass AM et al. | Nature Neuroscience | August 21, 2017
Skin suturing and cortical surface viral infusion improves imaging of neuronal ensemble activity with head-mounted miniature microscopes
In vivo optical imaging of neural activity provides important insights into brain functions at the single-cell level. Cranial windows and virally delivered calcium…
Li X et al. | Journal of Neuroscience Methods | August 19, 2017
Distinct Neural Circuits for the Formation and Retrieval of Episodic Memories
The formation and retrieval of a memory is thought to be accomplished by activation and reactivation, respectively, of the memory-holding cells (engram cells) by a…
Roy DS et al. | Cell | August 17, 2017
Multi-layer cortical calcium imaging in freely moving mice with prism probes and miniaturized fluorescence microscopy
In vivo circuit and cellular level functional imaging is a critical tool for understanding the brain in action. High resolution imaging of mouse cortical neurons with…
Gulati S et al. | JoVE | June 13, 2017
Dorsal-CA1 hippocampal neuronal ensembles encode nicotine-reward contextual associations
Natural and drug rewards increase the motivational valence of stimuli in the environment that, through Pavlovian learning mechanisms, become conditioned stimuli that…
Xia L et al. | Cell Reports | June 6, 2017