Anxiety Cells in a Hippocampal-Hypothalamic Circuit
The hippocampus is traditionally thought to transmit contextual information to limbic structures where it acquires valence. Using freely moving calcium imaging and…
Jimenez JC et al. | Neuron | January 31, 2018
Reward-Predictive Neural Activities in Striatal Striosome Compartments
The striatum has been shown to play a critical role in reward prediction. It is composed of two neurochemically and anatomically distinct compartments known as the…
Yoshizawa T et al. | eNeuro | January 29, 2018
Regulation of REM and Non-REM Sleep by Periaqueductal GABAergic Neurons
Mammalian sleep consists of distinct rapid eye movement (REM) and non-REM (NREM) states. The midbrain region ventrolateral periaqueductal gray (vlPAG) is known to be…
Weber F et al. | Nature Communications | January 24, 2018
Locus coeruleus input to hippocampal CA3 drives single-trial learning of a novel context
The memory for a new episode is formed immediately upon experience and can last up to a lifetime. It has been shown that the hippocampal network plays a fundamental role…
Wagatsuma A et al. | PNAS | December 26, 2017
Modulation of SF1 Neuron Activity Coordinately Regulates Both Feeding Behavior and Associated Emotional States
Feeding requires the integration of homeostatic drives with emotional states relevant to food procurement in potentially hostile environments. The ventromedial…
Viskaitis P et al. | Cell Reports | December 19, 2017
Combined Social and Spatial Coding in a Descending Projection from the Prefrontal Cortex
Social behaviors are crucial to all mammals. Although the prelimbic cortex (PL, part of medial prefrontal cortex) has been implicated in social behavior, it is not clear…
Murugan M et al. | Cell | December 7, 2017