Stress peptides sensitize fear circuitry to promote passive coping
Survival relies on optimizing behavioral responses through experience. Animals often react to acute stress by switching to passive behavioral responses when coping with…
Pliota P et al. | Molecular Psychiatry | June 18, 2018
The Striatum Organizes 3D Behavior via Moment-to-Moment Action Selection
Many naturalistic behaviors are built from modular components that are expressed sequentially. Although striatal circuits have been implicated in action selection and…
Markowitz JE et al. | Cell | May 17, 2018
Diametric neural ensemble dynamics in parkinsonian and dyskinetic states
Loss of dopamine in Parkinson's disease is hypothesized to impede movement by inducing hypo- and hyperactivity in striatal spiny projection neurons (SPNs) of the direct…
Parker JG et al. | Nature | May 2, 2018
The Same Hippocampal CA1 Population Simultaneously Codes Temporal Information over Multiple Timescales
It has long been hypothesized that a primary function of the hippocampus is to discover and exploit temporal relationships between events. Previously, it has been…
Mau W et al. | Current Biology | April 26, 2018
Neural Circuit Mechanisms of Social Behavior
We live in a world that is largely socially constructed, and we are constantly involved in and fundamentally influenced by a broad array of complex social interactions.…
Chen P et al. | Neuron | April 4, 2018
Encoding of Danger by Parabrachial CGRP Neurons
Animals must respond to various threats to survive. Neurons that express calcitonin gene-related peptide in the parabrachial nucleus (CGRPPBN neurons) relay sensory…
Campos CA et al. | Nature | March 21, 2018