CRF in BNST influences pain experience and behavior in a gender specific manner

Yu W et al. | Scientific Reports | June 14, 2021

LoTRA- a versatile algorithm for analyzing time-series data

Chomiak T et al. | NPJ Parkinson's Disease | November 9, 2021

DGCs' activity predicts auditory decisions after task learning

Shen J et al. | Scientific Reports | July 13, 2021

lVTA Vgat and Vglut2 projections onto dmCINs influence aversive stimuli…

Rizzi G et al. | Cell Reports | March 16, 2021

 Genetic identity of taste perceiving neurons

Jarvie BC et al. | Nature Communications | January 11, 2021
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Divergent medial amygdala projections regulate approach–avoidance conflict behavior

Avoidance of innate threats is often in conflict with motivations to engage in exploratory approach behavior. The neural pathways that mediate this approach–avoidance…

Miller SM et al. | Nature Neuroscience | February 25, 2019

A hypothalamus-habenula circuit controls aversion

Encoding and predicting aversive events are critical functions of circuits that support survival and emotional well-being. Maladaptive circuit changes in emotional…

Lazaridis I et al. | Molecular Psychiatry | February 12, 2019

Unsupervised discovery of temporal sequences in high-dimensional datasets, with applications to neuroscience

Identifying low-dimensional features that describe large-scale neural recordings is a major challenge in neuroscience. Repeated temporal patterns (sequences) are thought…

Mackevicius EL et al. | eLife | February 5, 2019

Dorsolateral septum somatostatin interneurons gate mobility to calibrate context-specific behavioral fear responses

Adaptive fear responses to external threats rely upon efficient relay of computations underlying contextual encoding to subcortical circuits. Brain-wide analysis of…

Besnard A et al. | Nature Neuroscience | February 4, 2019

Leveraging calcium imaging to illuminate circuit dysfunction in addiction

Alcohol and drug use can dysregulate neural circuit function to produce a wide range of neuropsychiatric disorders, including addiction. To understand the neural circuit…

Siciliano CA et al. | Alcohol | February 1, 2019

Intense threat switches dorsal raphe serotonin neurons to a paradoxical operational mode

Survival depends on the selection of behaviors adaptive for the current environment. For example, a mouse should run from a rapidly looming hawk but should freeze if the…

Seo C et al. | Science | January 31, 2019

bioRxiv Wire

Modulating D1 rather Yun S et al. | August 3, 2021

Overactive dopamine transmission in psychosis is predicted…

Transient dopamine Mendonça MD et al. | April 20, 2021

Dopamine neurons (DANs) in the substantia nigra pars…

Independent and distinct Manning EE et al. | March 3, 2021

Background Patients with obsessive-compulsive disorder (OCD…

An endogenous opioid Castro DC et al. | February 10, 2021

Mu-opioid peptide receptor (MOPR) stimulation alters…