General anesthetics activate a potent central pain-suppression circuit in the amygdala
General anesthesia (GA) can produce analgesia (loss of pain) independent of inducing loss of consciousness, but the underlying mechanisms remain unclear. We hypothesized…
Hua T et al. | Nature Neuroscience | May 18, 2020
Trajectory-modulated hippocampal neurons persist throughout memory-guided navigation
Trajectory-dependent splitter neurons in the hippocampus encode information about a rodent’s prior trajectory during performance of a continuous alternation task. As…
Kinsky NR et al. | Nature Communications | May 15, 2020
High-Throughput Task to Study Memory Recall During Spatial Navigation in Rodents
Spatial navigation is one of the most frequently used behavioral paradigms to study memory formation in rodents. Commonly used tasks to study memory are labor-intensive…
Morales L et al. | Frontiers in Behavioral Neuroscience | May 15, 2020
Ca2+ imaging of neurons in freely moving rats with automatic post hoc histological identification
Background Cognitive neuroscientists aim to understand behavior often based on the underlying activity of individual neurons. Recently developed miniaturized…
Anner P et al. | Journal of Neuroscience Methods | May 11, 2020
A neuronal signature for monogamous reunion
Pair-bond formation depends vitally on neuromodulatory signaling within the nucleus accumbens, but the neuronal dynamics underlying this behavior remain unclear. Using 1…
Scribner JL et al. | PNAS | May 7, 2020
Visualization and correction of social abnormalities-associated neural ensembles in adult MECP2 duplication mice
Duplications of MECP2-containing genomic segments led to severe autistic symptoms in male. Transgenic mice overexpressing the human MECP2 gene exhibit autistic-like…
Sun L et al. | Science Bulletin | April 26, 2020