Contextual fear memory retrieval by correlated ensembles of ventral CA1 neurons
Ventral hippocampal CA1 (vCA1) projections to the amygdala are necessary for contextual fear memory. Here we used in vivo Ca2+ imaging in mice to assess the temporal…
Jimenez JC et al. | Nature Communications | July 13, 2020
Precision Calcium Imaging of Dense Neural Populations via a Cell-Body-Targeted Calcium Indicator
Methods for one-photon fluorescent imaging of calcium dynamics can capture the activity of hundreds of neurons across large fields of view at a low equipment complexity…
Shemesh OA et al. | Neuron | June 26, 2020
Soma-Targeted Imaging of Neural Circuits by Ribosome Tethering
Neuroscience relies on techniques for imaging the structure and dynamics of neural circuits, but the cell bodies of individual neurons are often obscured by overlapping…
Chen Y et al. | Neuron | June 22, 2020
A Distributed Neural Code in the Dentate Gyrus and in CA1
Neurons are often considered specialized functional units that encode a single variable. However, many neurons are observed to respond to a mix of disparate sensory,…
Stefanini F et al. | Neuron | June 9, 2020
Heterogeneous Habenular Neuronal Ensembles during Selection of Defensive Behaviors
Optimal selection of threat-driven defensive behaviors is paramount to an animal’s survival. The lateral habenula (LHb) is a key neuronal hub coordinating behavioral…
Lecca S et al. | Cell Reports | June 9, 2020
Sparse Activity of Hippocampal Adult-Born Neurons during REM Sleep Is Necessary for Memory Consolidation
The occurrence of dreaming during rapid eye movement (REM) sleep prompts interest in the role of REM sleep in hippocampal-dependent episodic memory. Within the mammalian…
Kumar D et al. | Neuron | June 4, 2020