Model-based behavioral control can predict future states based on chosen actions
Akam T et al. | Neuron | November 4, 2020Functional clusters track parallel processing in direct and indirect pathways
Shin JH et al. | PNAS | October 27, 2020
Mouse fMRI reveals affective computations in a corticolimbic loop
Kargl D et al. | eLife | October 20, 2020
Identification of a key cellular component of sleep homeostasis in mice
Ingiosi AM et al. | Current Biology | September 24, 2020
Slow neuronal dynamics encode threat responses for emotional memory
Kennedy A et al. | Nature | September 16, 2020
Dichotomous dopaminergic and noradrenergic neural states mediate distinct aspects of exploitative behavioral states
The balance between exploiting known actions and exploring alternatives is critical for survival and hypothesized to rely on shifts in neuromodulation. We developed a…
Koralek AC et al. | Science Advances | July 23, 2021
Dentate granule cells encode auditory decisions after reinforcement learning in rats
Auditory-cued goal-oriented behaviors requires the participation of cortical and subcortical brain areas, but how neural circuits associate sensory-based decisions with…
Shen J et al. | Scientific Reports | July 13, 2021
Application of optogenetics and in vivo imaging approaches for elucidating the neurobiology of addiction
The neurobiology of addiction has been an intense topic of investigation for more than 50 years. Over this time, technological innovation in methods for studying brain…
Vickstrom CR et al. | Molecular Psychiatry | June 18, 2021
Head-mounted microendoscopic calcium imaging in dorsal premotor cortex of behaving rhesus macaque
Microendoscopic calcium imaging with one-photon miniature microscopes enables unprecedented readout of neural circuit dynamics during active behavior in rodents. In this…
Bollimunta A et al. | Cell Reports | June 15, 2021
Corticotropin-releasing factor neurons in the bed nucleus of the stria terminalis exhibit sex-specific pain encoding in mice
The bed nucleus of the stria terminalis (BNST) plays an emerging role in pain regulation. Pharmacological studies have found that inhibiting corticotropin-releasing…
Yu W et al. | Scientific Reports | June 14, 2021
A locus coeruleus to dentate gyrus noradrenergic circuit modulates aversive contextual processing
Dysregulation in contextual processing is believed to affect several forms of psychopathology, such as post-traumatic stress disorder (PTSD). The dentate gyrus (DG), a…
Seo D et al. | Neuron | June 2, 2021