Model-based behavioral control can predict future states based on chosen actions
Akam T et al. | Neuron | November 4, 2020Functional clusters track parallel processing in direct and indirect pathways
Shin JH et al. | PNAS | October 27, 2020
Mouse fMRI reveals affective computations in a corticolimbic loop
Kargl D et al. | eLife | October 20, 2020
Identification of a key cellular component of sleep homeostasis in mice
Ingiosi AM et al. | Current Biology | September 24, 2020
Slow neuronal dynamics encode threat responses for emotional memory
Kennedy A et al. | Nature | September 16, 2020
Optical deep-cortex exploration in behaving rhesus macaques
Non-human primates (NHPs) are important animal models for understanding higher brain functions relevant to complex human behaviors including cognition and motor control…
Matsuzaki M et al. | Nature Communications | August 2, 2021
Miniature microscopes for manipulating and recording in vivo brain activity
Here we describe the development and application of miniature integrated microscopes (miniscopes) paired with microendoscopes that allow for the visualization and…
Stamatakis AM et al. | Microscopy | August 2, 2021
Complete representation of action space and value in all dorsal striatal pathways
The dorsal striatum plays a central role in the selection, execution, and evaluation of actions. An emerging model attributes action selection to the matrix and…
Weglage M et al. | Cell Reports | July 27, 2021
Reverse optogenetics of G protein signaling by zebrafish non-visual opsin Opn7b for synchronization of neuronal networks
Opn7b is a non-visual G protein-coupled receptor expressed in zebrafish. Here we find that Opn7b expressed in HEK cells constitutively activates the Gi/o pathway and…
Karapinar R et al. | Nature Communications | July 23, 2021
Dichotomous dopaminergic and noradrenergic neural states mediate distinct aspects of exploitative behavioral states
The balance between exploiting known actions and exploring alternatives is critical for survival and hypothesized to rely on shifts in neuromodulation. We developed a…
Koralek AC et al. | Science Advances | July 23, 2021
Dentate granule cells encode auditory decisions after reinforcement learning in rats
Auditory-cued goal-oriented behaviors requires the participation of cortical and subcortical brain areas, but how neural circuits associate sensory-based decisions with…
Shen J et al. | Scientific Reports | July 13, 2021